Scientific Documents

Scientific Documents
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose induced metabolic dysfunction in rats
Scientific Documents
Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1H)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme
Scientific Documents
Synthesis And Biological Assessment of BUB1B Inhibitors for The Treatment of Clear Cell Renal Cell Carcinoma
Scientific Documents
Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies
Scientific Documents
Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins
Scientific Documents
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma
Scientific Documents
Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma.
Scientific Documents
Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
Scientific Documents
Unveiling Structural Features, Chemical Reactivity, and Bioactivity of a Newly Synthesized Purine Derivative through Crystallography and Computational Approaches
Scientific Documents
Trustlife Labs Pharmaceutical R&D Centre - Interviews
Scientific Documents
Discovery of Small Molecules As Potential Therapeutics For NAFLD and HCCBAU Conference Presentation
Scientific Documents
BioExpo 2023 Presentation - Computational Chemistry in Drug Discovery: Bridging the Gap from Lab to Clinic
Scientific Documents
Small Molecular inhibitors of Aurora kinase B; From Structural Insight to Mechanism Based Design
Scientific Documents
Exploring N-Ferrocenylmethylaniline Derivatives as Potent Anti-Breast Cancer Agents: Insights from Computational Chemistry, Pharmacokinetics, and QSAR Analysis
Scientific Documents
Tailoring Liver Pyruvate Kinase Inhibitors via Structural Guided Optimization
Scientific Documents
Drug Repositioning Targeting Glutaminase Reveals Drug Candidates for The Treatment of Alzheimer’s Disease Patients
Scientific Documents
Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase
Scientific Documents
Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma
Scientific Documents
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase
Scientific Documents
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Scientific Documents
Prediction of Drug Candidates for Clear Cell Renal Cell Carcinoma Using A Systems Biology-Based Drug Repositioning Approach
Scientific Documents
Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme
Scientific Documents
Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis
Scientific Documents
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development