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ALL CATEGORIES
Recent News
Scientific Documents
Patents
Blog
Interviews
Visits
Congresses
Investment News
Project Calls
Presantations
Visits
Visit of Minister of Health Prof. Dr. Kemal Memişoğlu to Trustlife
Scientific Documents
Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Scientific Documents
Novel pyrimidine derivatives as potent BUB1B inhibitors for clear cell renal cell carcinoma: From synthesis and characterization to docking insights and therapeutic validation
Scientific Documents
Phospho-JNK agonists show promising effects for the treatment of hepatocellular carcinoma
Scientific Documents
Multi-Target Neuroprotective Compound Exhibits EAAT2-Modulating and Alzheimer’s Pathology–Attenuating Effects in In Vitro and In Vivo Models
Recent News
Clinical Application for the First National Alzheimer’s Drug – Trustlife Press Release – 20.02.2026
Presantations
Trustlife 2025 Digital Impact Report
Presantations
Trustlife’s 2025 Activity Summary Report
Scientific Documents
Targeting PKLR in Liver Diseases
Congresses
Artificial Intelligence-Based Drug Development Panel-Bioexpo2025
Blog
Accurate Budgeting and Resource Allocation in Drug R&D: Trustlife’s Health Technologies Platform Model
Presantations
Investing in the Future of Medicine
Blog
Trustlife as an Innovative Health Technologies Platform: A Transformative and Collective Business Model
Recent News
WebsEdge Science-Rethinking Health and Disease Through Multi-Omics-Prof. Adil Mardinoglu
Blog
Future Drug Development Approaches: A New Era with Artificial Intelligence
Blog
Next-Generation Drug Safety: Cellular Responses, Toxicological Assessment, and Future Standards
Scientific Documents
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose induced metabolic dysfunction in rats
Scientific Documents
Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1H)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme
Scientific Documents
Synthesis And Biological Assessment of BUB1B Inhibitors for The Treatment of Clear Cell Renal Cell Carcinoma
Scientific Documents
Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies
Patents
Prostat Adenokarsinomu Tedavisi İçin Kullanima Uygun Yeni Etken Bileşikler
Patents
Prostat Adenokarsinom Hastalıklarının Tedavisinde Kullanıma Uygun Yeni Terapötik Hedef Gen ve Söz Konusu Terapötik Hedef Genlere Uygun Bir İlaç Adayı
Patents
Treatment of Lung Adenocarcinoma - PCT
Patents
Parbendazole For Use In The Treatment Of Dementia - PCT
Patents
Treatment of Lung Adenocarcinoma - EPO
Patents
Treatment of Dementia Using Bortezomib or Parbendazole - EPO
Investment News
Trustlife Ventures continues on its path with the investment of Alkima Partners (‘Alkima’).
Patents
New Therapeutic Target Gene Suitable for Use in TheTreatment of Prostate Adenocarcinoma Diseases and New Active Compounds Suitable for The Therapeutic Target Gene and Gene Products
Visits
Trustlife Scientific Leadership Visits Minister of Health
Patents
Small Molecule Treatment of Fatty Liver Disease and HCC -PCT
Patents
Small Molecule Treatment of Fatty Liver Disease and HCC - EPO
Scientific Documents
Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins
Scientific Documents
Discovery of A Therapeutic Agent for Glioblastoma Using A Systems Biology-Based Drug Repositioning Approach
Scientific Documents
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma
Scientific Documents
Novel Drug Targets and Molecular Mechanisms for Sarcopenia Based on Systems Biology
Scientific Documents
Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma
Scientific Documents
Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
Scientific Documents
Unveiling Structural Features, Chemical Reactivity, and Bioactivity of a Newly Synthesized Purine Derivative through Crystallography and Computational Approaches
Interviews
Bülent Denkdemir, CEO of Trustlife Ventures: At Trustlife, we conduct drug development studies using very advanced algorithms based on human data and artificial intelligence.
Congresses
Ten of our researchers attended the International Congress of Medicinal Chemistry
Recent News
Trustlife Labs Pharmaceutical R&D Centre: Drug Discovery and Development Process
Recent News
Another Award to Prof. Dr. Adil Mardinoğlu
Interviews
Trustlife Labs Pharmaceutical R&D Centre - Interviews
Visits
Main Consul of the United Kingdom in Istanbul and Undersecretary of Commerce for the Eastern Europe and Central Asia Network, Mr. Kenan Poleo visited Truslife.
Recent News
Trustlife 2023 Investment Fund Activity Report
Interviews
Trustlife, an SPK-approved venture capital investment fund, operates with a multidisciplinary approach aimed at bringing scientific research and innovative ideas together with investors.
Congresses
Bioexpo 2023 Panel: The Role of Artificial Intelligence in Drug Development
Recent News
Our scientific leader Prof. Dr. Adil Mardinoğlu has received the 100th Year Anniversary TÜBİTAK Special Science Award in recognition of his work and achievements in the fields of cell biology and molecular biology.
Presantations
Trustlife Corporate Infographic Presentation
Presantations
BioExpo 2023 Presentation - Computational Chemistry in Drug Discovery: Bridging the Gap from Lab to Clinic
Presantations
Discovery of Small Molecules As Potential Therapeutics For NAFLD and HCCBAU Conference Presentation
Presantations
Small Molecular inhibitors of Aurora kinase B; From Structural Insight to Mechanism Based Design
Presantations
Systems Biology & Artificial Intelligence Based Drug Development
Presantations
Exploring N-Ferrocenylmethylaniline Derivatives as Potent Anti-Breast Cancer Agents: Insights from Computational Chemistry, Pharmacokinetics, and QSAR Analysis
Presantations
Tailoring Liver Pyruvate Kinase Inhibitors via Structural Guided Optimization
Recent News
Trustlife Corporate Promotion
Presantations
Trustlife Turkey - Current Platform Structure
Interviews
Bioinformatics is a rewarding career in need of new recruits
Patents
New Compounds and Treatment of Renal Cell Carcinoma
Scientific Documents
Drug Repositioning Targeting Glutaminase Reveals Drug Candidates for The Treatment of Alzheimer’s Disease Patients
Scientific Documents
Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase
Scientific Documents
Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma
Scientific Documents
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase
Project Calls
Innovative Drug (Small Molecule) Development Project Call Results Announced
Project Calls
Trustlife Panelist Selection Has Been Made
Scientific Documents
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Project Calls
Trustlife Project Call Documentation Released
Project Calls
Project Call Theme Announced
Scientific Documents
Prediction of Drug Candidates for Clear Cell Renal Cell Carcinoma Using A Systems Biology-Based Drug Repositioning Approach
Scientific Documents
Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme
Scientific Documents
Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis
Scientific Documents
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development
![Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies](images/content/trsm006-a08_AWne.jpg)
![Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives](images/content/trsm006-a04_GQ6X.jpg)
