Bilimsel Yayınlar

Bilimsel Yayınlar
Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Bilimsel Yayınlar
Novel pyrimidine derivatives as potent BUB1B inhibitors for clear cell renal cell carcinoma: From synthesis and characterization to docking insights and therapeutic validation
Bilimsel Yayınlar
Phospho-JNK agonists show promising effects for the treatment of hepatocellular carcinoma
Bilimsel Yayınlar
Multi-Target Neuroprotective Compound Exhibits EAAT2-Modulating and Alzheimer’s Pathology–Attenuating Effects in In Vitro and In Vivo Models
Bilimsel Yayınlar
Targeting PKLR in Liver Diseases
Bilimsel Yayınlar
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose induced metabolic dysfunction in rats
Bilimsel Yayınlar
Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1H)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme
Bilimsel Yayınlar
Synthesis And Biological Assessment of BUB1B Inhibitors for The Treatment of Clear Cell Renal Cell Carcinoma
Bilimsel Yayınlar
Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies
Bilimsel Yayınlar
Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins
Bilimsel Yayınlar
Discovery of A Therapeutic Agent for Glioblastoma Using A Systems Biology-Based Drug Repositioning Approach
Bilimsel Yayınlar
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma
Bilimsel Yayınlar
Novel Drug Targets and Molecular Mechanisms for Sarcopenia Based on Systems Biology
Bilimsel Yayınlar
Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma
Bilimsel Yayınlar
Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
Bilimsel Yayınlar
Unveiling Structural Features, Chemical Reactivity, and Bioactivity of a Newly Synthesized Purine Derivative through Crystallography and Computational Approaches
Bilimsel Yayınlar
Drug Repositioning Targeting Glutaminase Reveals Drug Candidates for The Treatment of Alzheimer’s Disease Patients
Bilimsel Yayınlar
Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase
Bilimsel Yayınlar
Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma
Bilimsel Yayınlar
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase
Bilimsel Yayınlar
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Bilimsel Yayınlar
Prediction of Drug Candidates for Clear Cell Renal Cell Carcinoma Using A Systems Biology-Based Drug Repositioning Approach
Bilimsel Yayınlar
Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme
Bilimsel Yayınlar
Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis
Bilimsel Yayınlar
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development